Depression in the physical performance of the general headache, insomnia and other symptoms. At present, due to the rapid pace of life and the increasing number of depressed patients, due to various concerns, many domestic patients with depression do not want to admit that they are suffering from the disease. Depression can be compared to “mental flu,” a person’s life is likely to get several times such a “mental flu”, as long as the timely use of diet, pay attention to nutrition intake, the majority of patients will reduce or rehabilitation.
Depression patients tend to commit suicide when their condition is severe. French experts recently pointed out that the lack of nutrition is greatly linked to depression, a fact that has been largely ignored in past treatment. Monique Fellier, nutritionist at the Valens Medical Center in France, explains that when people lack nutrients, the brain can not get certain trace elements that are crucial to the brain’s production of neurotransmitters. Some studies have shown that the lack of neurotransmitters can easily lead to depression. On the other hand, poor appetite is one of the major symptoms of depression, as long-term lack of appetite leads to nutritional deficiencies, which further exacerbate depression.
Claude Jean-Dyer, head of the French geriatric specialist hospital, suggests that it is necessary to take early physical exams for people with depression and to prevent people from getting into nutritional deficits – depression – more nutritional deprivation – more degenerative malignancy Cycle; the same time, doctors in the treatment of patients with depression, care should be taken not to neglect the role of nutrition.
Some amino acids have neurotransmitter-like properties and therefore play an important role in the treatment of depression and anxiety disorders. Depression-related amino acids are phenylalanine, tryptophan, tyrosine, melatonin, adenosine methionine, ω-3 unsaturated fatty acids, etc., can not be synthesized in the body, must be from the diet In the supply.
Phenylalanine and tryptophan are important essential amino acids in human body, they are the precursors of norepinephrine and serotonin, which are neurotransmitters that regulate mood. Phenylalanine can improve the mood of most depressed patients. Previous studies found that taking low doses of phenylalanine 75 ~200 mg / d can alleviate depression. Another double-blind trial found that depression in patients with depression of 150 ~ 200mg / d Phenylalanine treatment is similar to antidepressants. Some doctors suggest that for patients with depression add 3-4 grams per day of phenylalanine a month, during which attention should be observed changes in blood pressure and headaches, insomnia and so on.
Depression in patients with brain serotonin levels are low, supplemented with amino acid can increase the synthesis of serotonin and melatonin, tryptophan and vitamins, nicotinic acid combination of the most obvious effect. Tryptophan (5-HTP) is more effective than tryptophan in relieving depression because it passes the blood-brain barrier with only 3% of oral tryptophan converted to serotonin, whereas 70% of oral 5-HTP is converted For serotonin. 5-HTP can also increase endorphins and other neurotransmitters, it can play a better antidepressant effect. Double-blind studies have shown that the antidepressant effect of 5-HTP is comparable to that of selective 5-HT recovery inhibitors (fluoxetine and levorprazole) and tricyclic drugs (imipramine and desipramine).
Tyrosine, in turn, catalyzes the production of norepinephrine via enzymatic action. Researchers used large doses of tyrosine (average 7 g / day) for depressed patients to reduce depression and whether high doses are needed to produce the best effect Not clear.
Melatonin from the conversion of tryptophan, beneficial to the treatment of seasonal affective disorder. Early double-blind studies suggested that taking a small amount of melatonin (0.125 mg three times daily) relieved winter depression. Patients with major depressive disorder often sleep disorders, melatonin is conducive to improving sleep and biological rhythm, especially for the maintenance of the sleep cycle is of great significance, but does not improve the antidepressant effect.
Tryptophan-rich foods are milk, millet, mushrooms, sea crabs, black sesame seeds, soybeans, pumpkin seeds, sunflower seeds, floss, tofu, eggs, etc., often supplement these foods, endocrine cells excrete melatonin.
S-Adenosylmethionine (SAM) is an endogenous methyl ligand that increases neurotransmitter synthesis, depressing patients with SAM-enriched foods and increasing serotonin and dopamine levels. Recent open studies of oral agents suggest that S-Adenosylmethionine is a potent antidepressant and well-tolerated drug.